Abstract 5: Analysis of Survival and Recurrences for Patients with Breast Cancer Receiving Mastectomy with or without Breast Reconstruction

نویسندگان

  • Charalampos Siotos
  • Ricardo J. Bello
  • Akachimere Uzosike
  • David M. Euhus
  • Michele A. Manahan
  • Carisa M. Cooney
  • Gedge D. Rosson
چکیده

CONCLUSIONS: For the first time, our results reveal a decrease of the stemness marker CD34 in murine skin cells in hypertrophic scars over time compared to unwounded skin. We are currently conducting single cell transcriptional analyses and functional studies on these fibroblasts to understand the heterogeneity of fibroblasts during hypertrophic scarring and the specific role of CD34+ fibroblasts in skin fibrosis. Our findings have promising therapeutic implications for the treatment of skin fibrosis.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2017